교원프로필

김상욱 사진
교원에 대한 정보를 나타내는 표입니다.
성명 김상욱
소속 생명과학과
전화번호 279-2348
E-mail sukim@postech.ac.kr
Homepage http://sbi.postech.ac.kr

학력

  • 1998.09 ~ 2002.08 FLORIDA STATE UNIVERSITY (박사-생물리학)
  • 1994.08 ~ 1996.08 고려대학교 (석사-생명공학)
  • 1988.03 ~ 1992.02 고려대학교 (학사-유전공학)

주요경력

  • 2002.09 ~ 2005.02 : UCLA
  • 1996.10 ~ 1998.06 : 한국과학기술연구원

전문분야

  • 생물정보학, 분자구조학, 단백질 구조예측
  • 세포막 단백질의 구조 기능 연구
  • 네트워크 생물학

학술지

국제전문학술지

  • Capicua suppresses hepatocellular carcinoma progression by controlling ETV4-MMP1 axis, HEPATOLOGY, , , - (2018)
  • Genetic analysis of hereditary gingival fibromatosis using whole exome sequencing and bioinformatics, Oral Diseases, , 23, 102-19 (2017)
  • Genetic alterations in mesiodens as revealed by targeted NGS and gene co-occurrence network analysis, ORAL DISEASES, , 23, 966-972 (2017)
  • March2 is required for Xenopus head organizer formation by antagonizing Wnt signaling pathway, MECHANISMS OF DEVELOPMENT, , 145, S63-S63 (2017)
  • Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak, MBIO, , 7, - (2016)
  • OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research, Oncotarget, , 7, 56147-56152 (2016)
  • Genetic analysis of hereditary gingival fibromatosis using whole exome sequencing and bioinformatics, Oral Diseases, , , - (2016)
  • Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, , , - (2016)
  • OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research, ONCOTARGET, , 7, 56147-56152 (2016)
  • Genetic Investigation of Bisphosphonate-Related Osteonecrosis of Jaw (BRONJ) via Whole Exome Sequencing and Bioinformatics, PLOS ONE, , 10, E0118084- (2015)
  • Metazoans evolved by taking domains from soluble proteins to expand intercellular communication network, Scientific Reports, , 5, - (2015)
  • Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases, PLOS ONE, , 10, E0136300- (2015)
  • RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 112, E4246-E4255 (2015)
  • Identification of cancer-type-specific modules comprised of cancer-type-specific variants through phenotype similarity between cancer types, PROTEIN SCIENCE, , 24, 266-266 (2015)
  • A comprehensive protein domain analysis to map cancer-type-specific somatic mutations, PROTEIN SCIENCE, , 24, 265-266 (2015)
  • Identification of transient protein complexes by using intrinsic disorder and network topology, PROTEIN SCIENCE, , 24, 258-259 (2015)
  • Computational Design of Binding Proteins to EGFR Domain II, PLOS ONE, , 9, - (2014)
  • Predictive combinatorial design of mRNA translation initiation regions for systematic optimization of gene expression levels, SCIENTIFIC REPORTS, , 4, - (2014)
  • Linear Motif-Mediated Interactions Have Contributed to the Evolution of Modularity in Complex Protein Interaction Networks, PLOS COMPUTATIONAL BIOLOGY, , 10, E1003881- (2014)
  • Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 111, E4458-E4467 (2014)
  • Investigation of Pathogenic Genes in Peri-Implantitis from Implant Clustering Failure Patients: A Whole-Exome Sequencing Pilot Study, PLOS ONE, , 9, - (2014)
  • Pyrilamine inhibits nicotine-induced catecholamine secretion, NEUROCHEMISTRY INTERNATIONAL, , 74, 42-45 (2014)
  • Predictive design of mRNA translation initiation region to control prokaryotic translation efficiency, METABOLIC ENGINEERING, , 15, 67-74 (2013)
  • Discovery of Cellular Proteins Required for the Early Steps of HCV Infection Using Integrative Genomics, PLOS ONE, , 8, E60333- (2013)
  • Rampant Exchange of the Structure and Function of Extramembrane Domains between Membrane and Water Soluble Proteins, PLOS COMPUTATIONAL BIOLOGY, , 9, E1002997- (2013)
  • Spatial and functional organization of mitochondrial protein network, SCIENTIFIC REPORTS, , 3, 1403- (2013)
  • A novel role for Gadd45 alpha in base excision repair: Modulation of APE1 activity by the direct interaction of Gadd45 alpha with PCNA, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, , 434, 185-190 (2013)
  • Protein design by fusion: implications for protein structure prediction and evolution, Acta Crystallographica Section D, , 69, 2451-2460 (2013)
  • Rewiring of PDZ domain-ligand interaction network contributed to eukaryotic evolution, PLOS GENETICS, , 8, -E1002510 (2012)
  • The protein interaction network of extracellular vesicles derived from human colorectal cancer cells, JOURNAL OF PROTEOME RESEARCH, , 11, 1144-1151 (2012)
  • Role of BI-1 (TEGT)-mediated ERK1/2 activation in mitochondria-mediated apoptosis and splenomegaly in BI-1 transgenic mice, Biochimica et Biophysica Acta - Molecular Cell Research, , 1823, 876-888 (2012)
  • PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin Receptors, JOURNAL OF BIOLOGICAL CHEMISTRY, , 287, 21012-21024 (2012)
  • Rational Engineering of Enzyme Allosteric Regulation through Sequence Evolution Analysis, PLOS COMPUTATIONAL BIOLOGY, , 8, E1002612-E1002612 (2012)
  • Network rewiring is an important mechanism of gene essentiality change, SCIENTIFIC REPORTS, , 2, - (2012)
  • Phenotypic characterization of peripheral T cells and their dynamics in scrub typhus patients, PLOS NEGLECTED TROPICAL DISEASES, , 6, - (2012)
  • Structural differences between thermophilic and mesophilic membrane proteins, PROTEIN SCIENCE, , 21, 1746-1753 (2012)
  • Evolutionary history of human disease genes reveals phenotypic connections and comorbidity among genetic diseases, SCIENTIFIC REPORTS, , 2, - (2012)
  • Both the Hydrophobicity and a Positively Charged Region Flanking the C-Terminal Region of the Transmembrane Domain of Signal-Anchored Proteins Play Critical Roles in Determining Their Targeting, PLANT CELL, , 23, 1588-1607 (2011)
  • Protein localization as a principal feature of the etiology and comorbidity of genetic diseases, MOLECULAR SYSTEMS BIOLOGY, , 7, - (2011)
  • Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression, PLOS COMPUTATIONAL BIOLOGY, , 7, - (2011)
  • OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research, PLOS ONE, , 6, - (2011)
  • Molecular Evolution of Protein Conformational Changes Revealed by a Network of Evolutionarily Coupled Residues, MOLECULAR BIOLOGY AND EVOLUTION, , 28, 2675-2685 (2011)
  • A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy, NATURE NANOTECHNOLOGY, , 6, 675-682 (2011)
  • Global Sequence Homology Detection Using Word Conservation Probability, Interdisciplinary Bio Central, , 3, 1-9 (2011)
  • A multifunctional core-shell nanoparticle for dendritic cell-based cancer immunotherapy, NATURE NANOTECHNOLOGY, , 6, 675-682 (2011)
  • Bax Inhibitor 1 Increases Cell Adhesion through Actin Polymerization: Involvement of Calcium and Actin Binding, MOLECULAR AND CELLULAR BIOLOGY, , 30, 1800-1813 (2010)
  • Global gene expression profile of Orientia tsutsugamushi, PROTEOMICS, , 10, 1699-1715 (2010)
  • ConPlex: a server for the evolutionary conservation analysis of protein complex structures., NUCLEIC ACIDS RESEARCH, , 38, W450-W456 (2010)
  • ConPlex: a server for the evolutionary conservation analysis of protein complex structures, NUCLEIC ACIDS RESEARCH, , 38, W450-W456 (2010)
  • Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice, PLOS ONE, , 5, - (2010)
  • CONSTRUCTION OF FUNCTIONAL INTERACTION NETWORKS THROUGH CONSENSUS LOCALIZATION PREDICTIONS OF THE HUMAN PROTEOME, JOURNAL OF PROTEOME RESEARCH, , 8, 3367-3376 (2009)
  • Integration of Evolutionary Features for the Identification of Functionally Important Residues in Major Facilitator Superfamily Transporters, PLOS COMPUTATIONAL BIOLOGY, , 5, E1000522-E1000522 (2009)
  • Evolutionary conservation in multiple faces of protein interaction, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, , 77, 14-25 (2009)
  • Bioinformatic approaches for the structure and function of membrane proteins, BMB REPORTS, , 42, 697-704 (2009)
  • Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants, BMC NEUROSCIENCE, , 9, - (2008)
  • Common occurrence of internal repeat symmetry in membrane proteins, PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, , 71, 68-80 (2008)
  • Transmembrane helix uniformity examined by spectral mapping of torsion angles, STRUCTURE, , 16, 787-797 (2008)
  • Functional analysis of dicer-2 missense mutations in the siRNA pathway of Drosophila, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, , 371, 525-530 (2008)
  • Expression of the novel wheat gene TM20 confers enhanced cadmium tolerance to bakers' yeast, JOURNAL OF BIOLOGICAL CHEMISTRY, , 283, 15893-15902 (2008)
  • Bax inhibitor-1 is a pH-dependent regulator of Ca2+ channel activity in the endoplasmic reticulum, JOURNAL OF BIOLOGICAL CHEMISTRY, , 283, 15946-15955 (2008)
  • Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order, COMPARATIVE AND FUNCTIONAL GENOMICS, , , - (2008)
  • Arabidopsis nuclear-encoded plastid transit peptides contain multiple sequence subgroups with distinctive chloroplast-targeting sequence motifs, PLANT CELL, , 20, 1603-1622 (2008)
  • Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation, PLOS PATHOGENS, , 4, - (2008)
  • THE SYNTHESIS AND HYDRAULIC PROPERTIES OF CALCIUM SULFO ALUMINATE(CSA) DERIVED FROM SECONDARY REFINING SLAG, JOURNAL OF THE KOREAN INSTITUTE OF METALS AND MATERIALS, , 46, 437-442 (2008)
  • Janus model of the Na,K-ATPase beta-subunit transmembrane domain: Distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization, JOURNAL OF MOLECULAR BIOLOGY, , 365, 706-714 (2007)
  • Engineering a de novo internal disulfide bridge to improve the thermal stability of xylanase from Bacillus stearothermophilus No. 236, JOURNAL OF BIOTECHNOLOGY, , 127, 300-309 (2007)
  • Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor beta chain gene, to airway hyper-responsiveness, CLINICAL AND EXPERIMENTAL ALLERGY, , 37, 592-598 (2007)
  • Transmembrane domain of myelin protein zero can form dimers: Possible implications for myelin construction, BIOCHEMISTRY, , 46, 12164-12173 (2007)
  • Functional characterization of sequence motifs in the transit peptide of Arabidopsis small subunit of Rubisco, PLANT PHYSIOLOGY, , 140, 466-483 (2006)
  • A limited universe of membrane protein families and folds, PROTEIN SCIENCE, , 15, 1723-1734 (2006)
  • Self-association of the transmembrane domain of an anthrax toxin receptor, JOURNAL OF MOLECULAR BIOLOGY, , 360, 145-156 (2006)
  • Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel, NATURE STRUCTURAL & MOLECULAR BIOLOGY, , 12, 113-119 (2005)
  • Transmembrane domain helix packing stabilizes integrin aIIb beta 3 in the low affinity state, JOURNAL OF BIOLOGICAL CHEMISTRY, , 280, 7294-7300 (2005)
  • Transmembrane glycine zippers: Physiological and pathological roles in membrane proteins, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 102, 14278-14283 (2005)
  • 2D SOLID STATE NMR SPECTRAL SIMULATION OF 3(10), ALPHA, AND PI-HELICES, JOURNAL OF MAGNETIC RESONANCE, , 168, 187-193 (2004)
  • A MODEL OF THE CLOSED FORM OF THE NICOTINIC ACETYLCHOLINE RECEPTOR M2 CHANNEL PORE, BIOPHYSICAL JOURNAL, , 87, 792-799 (2004)
  • Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, , 101, 5988-5991 (2004)
  • SNORKELING PREFERENCES FOSTER AN AMINO ACID COMPOSITION BIAS IN TRANSMEMBRANE HELICES, JOURNAL OF MOLECULAR BIOLOGY, , 339, 471-479 (2004)
  • The affinity of GXXXG motifs in transmembrane helix-helix interactions is modulated by long-range communication, JOURNAL OF BIOLOGICAL CHEMISTRY, , 279, 16591-16597 (2004)
  • Dynamical localization and partial-barrier localization in the Paul trap, PHYSICAL REVIEW E, , 61, 5124-5128 (2000)

국내전문학술지

  • Energy metabolism and whole-exome sequencing-based analysis of Sasang constitution: a pilot study, Integrative Medicine Research, , 6, 165-178 (2017)

일반학술지

  • PROTEIN-PROTEIN INTERACTION AND BIOLOGICAL NETWORK, BIOPHYSICAL SOCIETY NEWSLETTER, , 13, 3-9 (2008)
  • RETRIEVING PROTEIN DOMAIN ENCODING DNA SEQUENCES AUTOMATICALLY THROUGH DATABASE CROSS-REFERENCING, BIOINFORMATICS AND BIOSYSTEMS, , 1, 95-98 (2006)

학술회의논문

  • March2 is required for Xenopus head organizer formation by antagonizing Wnt signaling pathway, Mechanisms of Development, 0, 0, - (2017)
  • Prediction of post-translational phosphorylation of proteins using multiple kernel learning, The 7th internaltional conference of Korean Society for Bioinformatics, 0, 0, 16-21 (2006)

학회발표

  • Biological functions rather than individual genes can explain the phenotypic differences observed between human and mouse orthologous genes, 10th Annual RECOMB/ISCB Confernce on Regulatory & Systems Genomics, 0, 0, - (2017)
  • Identification of biomarkers and prediction of survival based on exome sequencing of the mouse model of aggressive bladder cancer, 10th Annual RECOMB/ISCB Confernce on Regulatory & Systems Genomics, 0, 0, - (2017)
  • A Golgi protein MON-2 mediates longevity conferred by reduced mitochondrial respiration in C. elegans , ., 0, 0, - (2017)
  • KIN-4/MAST kinase binds DAF-18/PTEN through its PDZ domain and contributes to the longevity of daf-2/insulin/IGF-1 receptor mutants , ., 0, 0, - (2017)
  • KIN-4/protein kinase influences insulin/IGF-1 signaling-mediated longevity via interacting with DAF-18/PTEN in C. elegans , ., 0, 0, - (2017)
  • Predicting the functional impact of protein mutations using coevolutionary signals, INTERNATIONAL CONFERENCE ON SYSTEMS BIOLOGY 2016, 0, 0, - (2016)
  • Types of domain mediated interaction explain gentype-phenotype relationships, INTERNATIONAL CONFERENCE ON SYSTEMS BIOLOGY 2016, 0, 0, - (2016)
  • Network evolution and phenotype changes between species, INTERNATIONAL CONFERENCE ON SYSTEMS BIOLOGY 2016, 0, 0, - (2016)
  • Popularity and similarity in network evolution explain the architecture of core/attachemnt in protein complexes, INTERNATIONAL SCHOOL AND CONFERENCE ON NETWORK SCIENCE 2016, 0, 0, - (2016)
  • Network evolution and understanding human gene-phenotype relationship, INTERNATIONAL SCHOOL AND CONFERENCE ON NETWORK SCIENCE 2016, 0, 0, - (2016)
  • Phenotype role of domain mediated interactions through community detection on the structural interaction network, INTERNATIONAL SCHOOL AND CONFERENCE ON NETWORK SCIENCE 2016, 0, 0, - (2016)
  • Identification of transient protein complexes by using intrinsic disorder and network topology, ., 0, 0, - (2015)
  • Identification of cancer-type-specific modules comprised of cancer-type-specific variants through phenotype similarity between cancer types, ., 0, 0, - (2015)
  • A comprehensive protein domain analysis to map cancer-type-specific somatic mutations, ., 0, 0, - (2015)
  • Protein complexes differ in the density and the modularity of protein-protein interactions to achieve, ., 0, 0, - (2015)
  • Weak linear motif-mediated interactions contribute to the rearrangement of modular architecture in complex protein interaction networks, ., 0, 0, - (2014)
  • Gene essentiality on model organism explains clinical severity of human genetic disorders, ., 0, 0, - (2014)
  • Domain exchange between membrane and soluble proteins contributes to expand intercellular communication network, ., 0, 0, - (2014)
  • Analysis of protein domains and gene essentiality, ., 0, 0, - (2014)
  • Domain exchange between membrane and soluble proteins contributes to metazoan evolution, ., 0, 0, - (2013)
  • Improving module identification in protein-protein interaction networks by using interaction strengths, ., 0, 0, - (2013)
  • Modular architecture of gene essentiality reveals clinical severity of human genetic diseases, ., 0, 0, - (2013)
  • Network Evolution and Gene Essentiality Changes, ., 0, 0, - (2013)
  • Fold Space and Function Annotation of Membrane Proteins, ., 0, 0, - (2013)
  • Analysis of shared structure and function between membrane and water-soluble proteins for drug design, ., 0, 0, - (2012)
  • Analysis of interaction strengths and global architecture in protein-protein interaction networks, ., 0, 0, - (2012)
  • Multipath in protein interaction network improved the understanding of the comorbidity of genetic diseases, ., 0, 0, - (2012)
  • Network medicine to predict drug side effects:Functional diversity of membrane proteins is mediated by dynamic rewiring of protein interactions, ., 0, 0, - (2012)
  • Global Sequence Homology Detection Using Word Conservation Probability, ., 0, 0, - (2011)
  • Comparative network analysis reveals the mechanism of gene essentiality changes, ., 0, 0, - (2011)
  • Evolutionary connections of disease modules implicate in the comorbidity, ., 0, 0, - (2011)
  • Evolution of domain-linear motif interactions shapes the modular architecture of protein-protein interaction networks, ., 0, 0, - (2011)
  • Connection patterns in protein-protein interaction network reveal the phenotypic relationships among human diseases, ., 0, 0, - (2011)
  • E-health for disease prognosis: Connection patterns in protein-protein interaction network reveal phenotype similarity and comorbidity of genetic diseases, ., 0, 0, - (2011)
  • E-health and network medicine: Network position can identify mitochondrial disease genes, ., 0, 0, - (2011)
  • Protein Localization as a principal feature of comorbidity, ., 0, 0, - (2011)
  • Comparative genomics between yeast and mouse reveals the etiology of genetic diseases, ., 0, 0, - (2011)
  • Network medicine to predict drug side effects: Rewiring of protein-protein interaction network of plasma membrane proteins explains drug side effects, ., 0, 0, - (2011)
  • Structural property of protein-protein interactions explains functional associations at the molecular and phenotypic levels, ., 0, 0, - (2011)
  • E-health and drug target discovery: Analysis of fold space of membrane proteins to find the template structures for drug target discovery, ., 0, 0, - (2011)
  • Membrane proteins share fold space with soluble proteins to expand their functional diversity during evolution, ., 0, 0, - (2011)
  • Tissue Specific Interactions of Plasma Membrane Proteins as the Mechanism of Functional Diversity, ., 0, 0, - (2010)
  • Protein conformational changes are derived from the network of evolutionarily coupled residues, ., 0, 0, - (2010)
  • Systematic analysis of human PDZ domain-ligand interaction network and their localization, ., 0, 0, - (2010)
  • The implications of protein subcellular localization for disease profiling, ., 0, 0, - (2010)
  • Systematic analysis of mitochondrial proteins involved in the communication to the cell, ., 0, 0, - (2010)
  • The important role of protein subcellular localization in disease profiling, ., 0, 0, - (2010)
  • Understanding the mitochondrial proteins involved in the communication to the cell through network biology, ., 0, 0, - (2010)
  • Comprehensive analysis of human PDZ domain-ligand interaction network, ., 0, 0, - (2010)
  • New insight into the fold space of membrane proteins revealed by structural comparison with soluble proteins, ., 0, 0, - (2010)
  • Tissue specific expression of plasma membrane proteins and their functional diversity, ., 0, 0, - (2010)
  • Insights into protein flexibility: The relationship between evolutionarily coupled residues and conformational changes, ., 0, 0, - (2010)
  • The importance of protein subcellular localization for disease profiling, ., 0, 0, - (2010)
  • Evolutionary analysis of conformational changes in allosteric proteins, ., 0, 0, - (2010)
  • Evolution of protein dynamics: Role of residue interaction networks in protein allostery, ., 0, 0, - (2009)
  • Quantitative interaction prediction revealed the genome-wide selectivity preferences of human PDZ domains, ., 0, 0, - (2009)
  • Identification of functional residues in Major Facilitator Superfamily (MFS) transporters using evolutionary features, ., 0, 0, - (2009)
  • Identification of eukaryote-specific mitochondrial proteome through data integration and phylogenetic profiling, ., 0, 0, - (2009)
  • Functional and evolutionary relationship between membrane and soluble proteins, ., 0, 0, - (2009)
  • Bioinformatic studies of protein sequence, structure, and function, ., 0, 0, - (2009)
  • Intrinsically unstructured C-terminal regions of transmembrane PDZ ligands play an important role in clustering scaffold proteins, ., 0, 0, - (2009)
  • Analysis of eukaryote-specific mitochondrial protein networks through data integration and phylogenetic profiling, ., 0, 0, - (2009)
  • Genome-wide selectivity preferences of human PDZ domain-ligand interactions, ., 0, 0, - (2009)
  • Identification of eukaryote-specific mitochondrial proteome through data integration and phylogenetic profiling, ., 0, 0, - (2009)
  • Functional and evolutionary relationship between membrane and soluble proteins, ., 0, 0, - (2009)
  • Assessing systems properties of human mitochondria through a quantitative proteomics analysis, ., 0, 0, - (2009)
  • A new systematic approach to identify functions of human extracellular proteins using yeast, ., 0, 0, - (2009)
  • Rational design of binding determinant specific non-antibody protein scaffolds: EGFR inhibitors with novel mechanism of action, ., 0, 0, - (2009)
  • Intrinsically unstructured C-terminal regions of transmembrane PDZ ligands play an important role in clustering scaffold proteins, ., 0, 0, - (2009)
  • Evolutionary conservation in multiple face of protein interaction, ., 0, 0, - (2009)
  • Protein interface design to generate novel binder proteins, The 6th Proteome Biophysics workshop, 0, 0, - (2008)
  • Evolutionary conservation in multiple faces of protein interaction, 2008 YBRI-KIAS international symposium of protein structure and function, 0, 0, - (2008)
  • Locally fluctuating ligand-binding residues transfer ligand binding signals to distal sites via co-evolved pathway, 2008 YBRI-KIAS international symposium of protein structure and function, 0, 0, - (2008)
  • Quantitative interation prediction revealed the genome-wide selectivity preferences of human PDZ domains, 2008 YBRI-KIAS international symposium of protein structure and function, 0, 0, - (2008)
  • Large-scale Analysis of Protein Complexes Reveals Evolutionary Conservation in Multiple faces of Protein interaction, The 9th International Congress on Cell Biology, 0, 0, - (2008)
  • Locally fluctuating ligand-binding residues transfer ligand binding signals to distal sites via co-evolved pathway, ., 0, 0, - (2008)
  • Quantitative interaction prediction revealed the genome-wide selectivity preferences of human PDZ domains, ., 0, 0, - (2008)
  • Large-scale Analysis of Protein Complexes Reveals Evolutionary Conservation in Multiple faces of Protein interaction, ., 0, 0, - (2008)
  • Integrative proteomics analysis of human mitochondrial protein functional network in normal and dysfunctional states, The 22nd symposium of the protein society, 0, 0, - (2008)
  • Systematic Integration of Proteomics and Bioinformatics Reveals the Evolutionary Modularity of Human Mitochondrial Protein Functional Network., From Bench to Clinic : Mitochondria and Metabolic Diseases, 0, 0, - (2008)
  • Structural Bioinformatics Studies of Protein-Protein interaction network, 2008 Korean Biophysical Society Meeting, 0, 0, - (2008)
  • A comparative mitochondrial proteomics of human 143B TK osteosarcoma cells upon mitochondrial DNA depletion using ICAT and LC/MS/MS, 8th International Proteomics Conference, 0, 0, - (2008)
  • Assessing systems property of human mitochondrial protein functional network by using integrative proteomics and bioinformatics, 8th international Proteomics Conference, 0, 0, - (2008)
  • Large-scale analysis of protein complexes reveals evolutionary conservation in multiple faces of protein interaction., The 65th KSBMB Annual Meeting in 2008, 0, 0, - (2008)
  • Assessing systems properties of human protein functional network by an integrated proteomics and bioinformatics approach, The 25th Korean sociey for cell biology symposium, 0, 0, - (2008)
  • Structure Comparison by use of Geometric Hashing, The 7th Protein Folding School, 0, 0, - (2008)
  • Prediction of functional residues in major facilitator superfamily transporters using integrated evolutionary features, The Sixth Asia Pacific Bioinformatics Conference 2008, 0, 0, - (2008)
  • Structural bioinformatics of membrane proteins and protein-protein interactions, The 4th Molecular Computation Initiative Workshop, 0, 0, - (2007)
  • Bioinformatics approaches of Mitochondrial ion channel discovery, 2nd symposium of Korean society for Mitochondrial Research and Medicine, 0, 0, - (2007)
  • Discovery of novel mitochondrial membrane proteins by systematic data integration, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Finding amino acid patterns in protein localization, The 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Identification of ligand binding site in eukaryotic translation initiation factor 4A by docking study, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Identification of the functinal network components in tumor derived microvesicles, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Missing puzzles in current proteome researches; the membrane protein functionomics, The 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Reorganizing protein functional network based on the consensus localization prediction, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Specificity prediction of PDZ domain using machine learning technique, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (2007)
  • Specificity prediction of PDZ domain using kernel based machine learning, IEEE international conference on Bioengineering & Bioinformactics, 0, 0, - (2007)
  • Prediction of membrane protein structures and functions by using bioinformatics, Protein Structure, Interaction, Stability and Function Workshop, 0, 0, - (2007)
  • Detecting the ligand selectivity of sub-family proteins by using evolutionary conserved and functionally coevolved residues, European Symposium of the Protein Society, 0, 0, - (2007)
  • Identification of functional residues in Major Facilitator Superfamily (MFS) transporters using evolutionary information, European Symposium of the Protein Society, 0, 0, - (2007)
  • Structural Bioinformatics of membrane proteins and protein-protein interactions, The 6th China-Japan-Korea Bioinformatics training course, 0, 0, - (2007)
  • Specificity prediction of PDZ domain using kernel based machine learning, The fifth aisa pacific bioinformatics conference, 0, 0, - (2007)
  • Bioinformatics approach to study membrane protein structure and function, Current topics in biomedical sciences, 0, 0, - (2006)
  • modeling membrane protein structure and function, The 7th international conference of Korean society for Bioinformatics, 0, 0, - (2006)
  • Modeling structure and function of membrane proteins, 2006 Asia Pacific summer school on computational biology, 0, 0, - (2006)
  • Internal sequence repeats and structural symmetry in membrane proteins, 50th Biophysical Society Annual Meeting, 0, 0, - (2006)
  • Structural bioinformatics studies of membrane protein folding and functional mechanism, Membrane Protein Symposium, 0, 0, - (2006)
  • Membrane protein structure and functional prediction, The 7th Northeastern Asia Symposium on Biotechnology, 0, 0, - (2005)
  • Membrane protein structure prediction using symmetry information and clustering, The Fifth KIAS Conference on Protein Structure and Function, 0, 0, - (2005)
  • Structural bioinformatics study of membrane proteins, New Trends in Bio-Science ""International symposium with KSMCB"", 0, 0, - (2005)
  • Structural bioinformatics study on transmembrane signaling, Annual Meeting of Korean Society for Biochemistry and Molecular Biology, 0, 0, - (2005)
  • Structural bioinformatics study on transmembrane signaling, Annual Meeting of Korean Society for Biochemistry and Molecular Biology, 0, 0, - (0000)
  • Membrane protein structure and functional prediction, The 7th Northeastern Asia Symposium on Biotechnology, 0, 0, - (0000)
  • Structural bioinformatics study of membrane proteins, New Trends in Bio-Science ""International symposium with KSMCB"", 0, 0, - (0000)
  • Membrane protein structure prediction using symmetry information and clustering, The Fifth KIAS Conference on Protein Structure and Function, 0, 0, - (0000)
  • Structural bioinformatics studies of membrane protein folding and functional mechanism, Membrane Protein Symposium, 0, 0, - (0000)
  • Internal sequence repeats and structural symmetry in membrane proteins, 50th Biophysical Society Annual Meeting, 0, 0, - (0000)
  • Modeling structure and function of membrane proteins, 2006 Asia Pacific summer school on computational biology, 0, 0, - (0000)
  • modeling membrane protein structure and function, The 7th international conference of Korean society for Bioinformatics, 0, 0, - (0000)
  • Bioinformatics approach to study membrane protein structure and function, Current topics in biomedical sciences, 0, 0, - (0000)
  • Specificity prediction of PDZ domain using kernel based machine learning, The fifth aisa pacific bioinformatics conference, 0, 0, - (0000)
  • Structural Bioinformatics of membrane proteins and protein-protein interactions, The 6th China-Japan-Korea Bioinformatics training course, 0, 0, - (0000)
  • Detecting the ligand selectivity of sub-family proteins by using evolutionary conserved and functionally coevolved residues, European Symposium of the Protein Society, 0, 0, - (0000)
  • Identification of functional residues in Major Facilitator Superfamily (MFS) transporters using evolutionary information, European Symposium of the Protein Society, 0, 0, - (0000)
  • Prediction of membrane protein structures and functions by using bioinformatics, Protein Structure, Interaction, Stability and Function Workshop, 0, 0, - (0000)
  • Specificity prediction of PDZ domain using kernel based machine learning, IEEE international conference on Bioengineering & Bioinformactics, 0, 0, - (0000)
  • Discovery of novel mitochondrial membrane proteins by systematic data integration, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Finding amino acid patterns in protein localization, The 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Identification of ligand binding site in eukaryotic translation initiation factor 4A by docking study, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Identification of the functinal network components in tumor derived microvesicles, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Missing puzzles in current proteome researches; the membrane protein functionomics, The 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Reorganizing protein functional network based on the consensus localization prediction, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Specificity prediction of PDZ domain using machine learning technique, 8th International Conference of Korean Society for Bioinformatics, 0, 0, - (0000)
  • Bioinformatics approaches of Mitochondrial ion channel discovery, 2nd symposium of Korean society for Mitochondrial Research and Medicine, 0, 0, - (0000)
  • Structural bioinformatics of membrane proteins and protein-protein interactions, The 4th Molecular Computation Initiative Workshop, 0, 0, - (0000)
  • Prediction of functional residues in major facilitator superfamily transporters using integrated evolutionary features, The Sixth Asia Pacific Bioinformatics Conference 2008, 0, 0, - (0000)
  • Structure Comparison by use of Geometric Hashing, The 7th Protein Folding School, 0, 0, - (0000)
  • Assessing systems properties of human protein functional network by an integrated proteomics and bioinformatics approach, The 25th Korean sociey for cell biology symposium, 0, 0, - (0000)
  • Large-scale analysis of protein complexes reveals evolutionary conservation in multiple faces of protein interaction., The 65th KSBMB Annual Meeting in 2008, 0, 0, - (0000)
  • A comparative mitochondrial proteomics of human 143B TK osteosarcoma cells upon mitochondrial DNA depletion using ICAT and LC/MS/MS, 8th International Proteomics Conference, 0, 0, - (0000)
  • Assessing systems property of human mitochondrial protein functional network by using integrative proteomics and bioinformatics, 8th international Proteomics Conference, 0, 0, - (0000)
  • Structural Bioinformatics Studies of Protein-Protein interaction network, 2008 Korean Biophysical Society Meeting, 0, 0, - (0000)
  • Systematic Integration of Proteomics and Bioinformatics Reveals the Evolutionary Modularity of Human Mitochondrial Protein Functional Network., From Bench to Clinic : Mitochondria and Metabolic Diseases, 0, 0, - (0000)
  • Integrative proteomics analysis of human mitochondrial protein functional network in normal and dysfunctional states, The 22nd symposium of the protein society, 0, 0, - (0000)
  • Large-scale Analysis of Protein Complexes Reveals Evolutionary Conservation in Multiple faces of Protein interaction, The 9th International Congress on Cell Biology, 0, 0, - (0000)
  • Evolutionary conservation in multiple faces of protein interaction, 2008 YBRI-KIAS international symposium of protein structure and function, 0, 0, - (0000)
  • Locally fluctuating ligand-binding residues transfer ligand binding signals to distal sites via co-evolved pathway, 2008 YBRI-KIAS international symposium of protein structure and function, 0, 0, - (0000)
  • Quantitative interation prediction revealed the genome-wide selectivity preferences of human PDZ domains, 2008 YBRI-KIAS international symposium of protein structure and function, 0, 0, - (0000)
  • Protein interface design to generate novel binder proteins, The 6th Proteome Biophysics workshop, 0, 0, - (0000)

단행본

  • From Topology to High Resolution Memebrane Proteins Structures. In Perspectives on Solid State NMR in Biology, Kluwer Academic Publishers, , 김상욱 (2001)

연구실적

  • 세포막 단백질의 조합 구조예측, 포항공과대학교 (2005-2006)
  • 생물학연구정보센터 2005년 연구비, 한국과학재단 (2005-2006)
  • 생물학정보센터 관련기관 운영비 지원금, 국립암센터 (2005-2008)
  • 세포막 단백질의 구조와 기능 예측, 포항공과대학교 (2006-2007)
  • 생물학연구정보센터 특별지원금, 포항공과대학교 (2006-2007)
  • 컴퓨터를 이용한 이스트-투 하이브리드 시스템의 개발, 한국학술진흥재단 (2006-2007)
  • 생물학연구정보센터 2006년도 연구비, 한국과학재단 (2006-2007)
  • 생물학연구정보센터 2007년도 연구비, 한국과학재단 (2007-2008)
  • 생명과학 학술정보 수집 및 메타 데이터베이스 구축, 한국과학기술정보연구원 (2007-2007)
  • BT분야 E-SCIENCE 보급, 커뮤니티 활성화 및 포털 사이트 구축, 한국과학기술정보연구원 (2007-2007)
  • 바이오인포매틱스 기법을 이용한 미토콘드리아 막단백과 이온채널 발굴 및 기능 연구, 충남대학교 (2007-2008)
  • 연구실안전관리비 적립과제, 한국과학재단 (2007-2015)
  • BIOWORKS 성과확산 및 동적 바이오정보 모니터링 시스템 구축, 한국과학기술정보연구원 (2008-2008)
  • 인건비풀링과제, 포항공과대학교 (2008-2015)
  • 자체연구개발과제, 포항공과대학교 (2008-2016)
  • 바이오인포매틱스 기법을 이용한 미토콘드리아 막단백과 이온채널 발굴 및 기능 연구, 충남대학교 (2008-2009)
  • 생물학연구정보센터, 한국과학재단 (2009-2010)
  • 4.2711(08년도) 이월과제-생물학연구정보센터, 한국과학재단 (2009-2010)
  • ORIENTIA의 기능 유전체 DB구축 및 분석, 서울대학교 산학협력단 (2009-2010)
  • HOMEODOMAIN 결합 DNA MOTIF의 예측과 REGULATORY NETWORK의 구축, (재)한국과학창의재단 (2009-2009)
  • 바이오인포메틱스 기법을 이용한 질병관련 미토콘드리아 단백질 발굴 및 기능 연구, 충남대학교산학협력단 (2009-2010)
  • (학생)인건비풀링과제, 포항공대산학협력단 (2009-2020)
  • 단백질 발현양의 정밀한 조절 메커니즘 연구(학부생연구프로그램), 포항공과대학교 (2009-2010)
  • 생물학연구정보센터(2010), 재단법인한국연구재단 (2010-2011)
  • ORIENTIA의 기능 유전체 DB 구축 및 분석, 서울대학교 산학협력단 (2010-2011)
  • 바이오인포메틱스 기법을 이용한 질병관련 미토콘드리아 단백질 발굴 및 기능 연구, 충남대학교산학협력단 (2010-2011)
  • 생물학연구정보센터, 재단법인한국연구재단 (2011-2012)
  • 통신네트워크와 생체회로 융합 연구, 포항공대산학협력단 (2011-2012)
  • 운동에 따른 조직특이적 네트워크이 리모델링 연구(학부생-김성현/생명), 포항공과대학교 (2011-2011)
  • 바이오인포메틱스 기법을 이용한 질병관련 미토콘드리아 단백질 발굴 및 기능 연구, 충남대학교산학협력단 (2011-2012)
  • 생물학연구정보센터, 재단법인한국연구재단 (2012-2013)
  • 생체분자 네트워크 기반 질병 모듈 분석을 통한 질병 유전자 발굴과 공존질환 예측 방법 개발, 재단법인한국연구재단 (2012-2013)
  • IT-BT 융합 기술 개발을 통한 의료기록 저장, 탐색, 분석 선진화 연구, 포항공과대학교 (2013-2014)
  • 생물학연구정보센터, 재단법인한국연구재단 (2013-2014)
  • 생체분자 네트워크 기반 질병 모듈 분석을 통한 질병 유전자 발굴과 공존질환 예측 방법 개발, 재단법인한국연구재단 (2013-2014)
  • (김동효-생명)유전자 파트너의 네트워크 위상학적 특성 변화가 미치는 ESSENTIALITY, 포항공과대학교 (2013-2013)
  • (김상욱)BSRI_융합기술을 통한 생체네트워크구축과 치료기술 개발, 포항공과대학교 (2014-2015)
  • 생물학연구정보센터, 재단법인한국연구재단 (2014-2015)
  • 생체분자 네트워크 기반 질병 모듈 분석을 통한 질병 유전자 발굴과 공존질환 예측 방법 개발, 재단법인한국연구재단 (2014-2015)
  • 4.9605_1단계 1차년도 이월과제, 재단법인한국연구재단 (2014-2015)
  • R_직접비_10022362_CLUSTER SYSTEM, 포항공과대학교 (2015-2020)
  • (BRSI-ISP)빅데이터 분석과 네트워크 연구를 위한 다학제간 스터디 포럼, 포항공과대학교 (2015-2016)
  • 생물학연구정보센터, 재단법인한국연구재단 (2015-2016)
  • [학생연구프로그램_신중한]단백질 네트워크 분석을 통한 인간 질병 표현형의 이해, 포항공과대학교 (2015-2015)
  • 단백질 상호작용 네트워크 모듈분석을 통한 유전자-질병 프로파일 구축, 재단법인한국연구재단 (2015-2016)
  • 미토콘드리아 매개 사상체질 진단을 위한 유전체 분석, 한국한의학연구원 (2015-2015)
  • 환경변화에 대응한 오믹스 기반 수산생물 감염성질병 제어기술 개발, 해양수산과학기술진흥원 (2015-2016)
  • 자체연구개발과제[2015년 신설], 포항공과대학교 (2015-2035)
  • 2015년 기술영향평가대상기술(유전자가위기술)온라인설문조사용역, 한국과학기술기획평가원 (2015-2015)
  • 미토콘드리아 매개 사상체질 진단을 위한 유전체 분석, 한국한의학연구원 (2016-2016)
  • 나고야의정서(ABS)발효의 대응방안을 위한 연구자 인식조사, 한국생명공학연구원 (2016-2016)
  • S_직접비_김상욱, 포항공과대학교 (2016-2020)
  • 생물학연구정보센터, 재단법인한국연구재단 (2016-2017)
  • 단백질 상호작용 네트워크 모듈분석을 통한 유전자-질병 프로파일 구축, 재단법인한국연구재단 (2016-2017)
  • 4.12360_이월과제, 재단법인한국연구재단 (2016-2017)
  • 환경변화에 대응한 오믹스 기반 수산생물 감염성질병 제어기술 개발, 부산대학교 (2016-2017)
  • 나고야의정서 비준 대비 연구자 인식조사, 한국생명공학연구원 (2017-2017)
  • 생물학연구정보센터, 재단법인한국연구재단 (2017-2018)
  • 단백질 상호작용 네트워크 모듈분석을 통한 유전자-질병 프로파일 구축, 재단법인한국연구재단 (2017-2018)
  • (집담회)IT,BT융합 기술을 통한 의료빅데이터 분석과 질병유전자 발굴, 포항공과대학교 (2017-2018)
  • 후성유전학 기반 네트워크 생물학 연구인력양성, 재단법인한국연구재단 (2017-2018)
  • 환경변화에 대응한 오믹스 기반 수산생물 감염성질병 제어기술 개발, 부산대학교 (2017-2018)
  • 나고야의정서 및 유전자원법 인식도조사, 한국생명공학연구원 (2018-2018)
  • 후성유전학 기반 네트워크 생물학 연구인력양성, 재단법인한국연구재단 (2018-2018)
  • 생물학연구정보센터, 재단법인한국연구재단 (2018-2018)
  • 생체 네트워크의 링크 교란 정량화를 통한유전자-질병표현형 프로파일의 구축, 재단법인한국연구재단 (2018-2019)
  • 환경변화에 대응한 오믹스 기반 수산생물 감염성질병 제어기술 개발, 부산대학교 (2018-2019)
  • 생물학연구정보센터, 재단법인한국연구재단 (2018-2019)
  • 4.15021 이월과제, 재단법인한국연구재단 (2018-2018)
  • 나고야의정서 인식도 조사, 한국생명공학연구원 (2018-2018)
  • 후성유전학 기반 네트워크 생물학 연구인력양성, 재단법인한국연구재단 (2019-2019)
  • 생체 네트워크의 링크 교란 정량화를 통한유전자-질병표현형 프로파일의 구축, 재단법인한국연구재단 (2019-2020)
  • 생물학연구정보센터, 재단법인한국연구재단 (2019-2020)

IP

  • 김상욱,황지혜,최윤섭, 약물 표적 막 단백질 안정성 테스트 기술 개발, 한국, 10-2014-0020441 (2013)
  • 김상욱,황지혜,최윤섭, 약물 표적 막 단백질 안정성 테스트 기술 개발, 한국, 10-2014-0020441 (2013)
  • 류성호,최윤섭,정준호,김상욱,조현수,윤수민,김경록,유지호, 표적 특이적 비항체-바인더 단백질의 합리적 디자인 방법, 중국, 2010800206288 (2011)
  • 류성호,최윤섭,정준호,김상욱,조현수,윤수민,김경록,유지호, 표적 특이적 비항체-바인더 단백질의 합리적 디자인 방법, 중국, 201080020628.8 (2011)
  • 류성호,최윤섭,정준호,김상욱,조현수,윤수민,김경록,유지호, 표적 특이적 비항체-바인더 단백질의 합리적 디자인 방법, 중국, 201080020628.8 (2011)
  • 류성호,최윤섭,정준호,김상욱,조현수,윤수민,김경록,유지호, 표적 특이적 비항체-바인더 단백질의 합리적 디자인 방법, 일본, 2012-505820 (2011)
  • 류성호,최윤섭,정준호,김상욱,조현수,윤수민,김경록,유지호, 표적 특이적 비항체-바인더 단백질의 합리적 디자인 방법, 일본, 2012-505820 (2011)
  • 류성호,최윤섭,정준호,김상욱,조현수,윤수민,김경록,유지호, 표적 특이적 비항체-바인더 단백질의 합리적 디자인 방법, USA, 13/264,365 (2011)
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