TGFβ ligands belonging to the Activin/Nodal family, induces mesoderm and endoderm, specifies the embryonic axes, promotes gastrulation movements, maintains pluripotency of embryonic stem cells, and determines left-right asymmetry in vertebrates. Activin/Nodal ligands signal through type I and type II transmembrane serine/threonine kinase receptors. Ligand binding induces the formation of heteromeric receptor complexes in which type II receptors phosphorylate and activate type I receptors. The activated type I receptors transduce the signal inside the cell through the phosphorylation of th..

A research team of Department of Life Science’s Center for Biomolecular Recognition and Division of Molecular and Life Science, consisting of Professor Byung-Ha Oh, Doctor Jae-Sung Woo, and Doctor Jae-Hong Lim, has solved secrets of the ring-shaped molecular structure of the MukBEF condensin, the key mediator of chromosome condensation.In eukaryotic organisms, chromosomes are found in the nucleus of every cell. Before cell division, chromosomes are condensed, and the two replicated copies of the chromosomes are partitioned into the two daughter cells. In prokaryotic organisms, chromosome..

Spin-valve devices are a key component of a magnetoresistive random access memory. Mr. Woo Youn Kim and Professor Kwang Soo Kim of Department of Chemistry of POSTECH predicted supermagnetoresistance in a graphene nanoribbon device, the article of which has appeared in Nature Nanotech (3, 408-412, 2008). The reported graphene nanoribbon spin-valve device shows extremely large magnetoresistance (ten thousand times larger than that of conventional devices), which promises high speed access, and good sensitivity. The striking enhancement originates from the peculiar symmetry of band structures of ..

X-ray imaging shows in real-time and in in-vivo that intensive irradiation of x-rays significantly decreases the surface tension of water in droplets and capillary tubes. X-rays are used in a variety of experimental studies of liquids, in particular, of water. The present synchrotron sources allow intense irradiation, possibly enabling to alter the basic property of surface tension. In spite of its potential impact, this issue has been still unexplored. In 1896 Wilson roughly showed that x-rays ionized the air molecules, and the electrons and ions created cloud nuclei in a cloud chamber. His c..